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doi: 10.1074/jbc.270.22.13138 92 PedruzziEHakimJGiroudJPPerianinA

Functional heterogeneity expresses itself via differences in metabolism, oxygen supply, b-oxidation, amino acid metabolism, gluconeogenesis, glycolysis, ureagenesis, liponeogenesis, and bile acid and bilirubin secretion

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Because the mechanisms don't overlap, some patients use them together as parts of one supervised plan

Having ups and downs is part of the process, says Dr