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Statements Data availability statement The datasets generated for this study can be found in the GenBank accession numbers: MH794462 and MH794463

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doi: 10.1021/tx990155o

dose-dependent response across 3, 6, and 9 mg arms Phase 3 T2D : HbA1c reductions up to 2.15% versus placebo in Chinese population trials Phase 1b/2 data : Earlier dose-finding studies establishing the efficacy and tolerability profile Global development : Ongoing clinical trials outside China, but no FDA approval or submission as of early 2026 Limitation : Primary clinical data from Chinese population