The reasons were structural: Supply was fragmented across thousands of small private practices, billing was opaque, and most patients were unaware the benefit even existed
FDA labels note that dehydration from gastrointestinal adverse effects can contribute to acute kidney injury in some cases
Gentle swirling is all that's needed
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The concept of such a drug was not new
The search strategy was based on a combination of keywords and subject headings, including: breast cancer, breast cancer and oxidative stress, breast cancer prevalence, reactive oxygen species in breast cancer, cancer statistics, medicinal plants in breast cancer treatment, dietary antioxidants and breast cancer, and antioxidants in breast cancer treatment. After the initial search, duplicate records were removed and the remaining studies were subjected to a two-stage screening process
