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Insulin Dose Reduction at GLP-1 RA Initiation In the SUSTAIN-5 trial (N=397), patients on semaglutide 1 mg plus basal insulin experienced a symptomatic hypoglycemia rate of 11.3%, versus 1.1% in the semaglutide-plus-metformin-only arm [6]

Eating smaller, more frequent meals can also help to reduce nausea

These programs are designed specifically for patients who either lost coverage or never had it

[1] [3] It is metabolised by proteolytic breakdown and beta-oxidation, with the resulting metabolites excreted in urine and faeces

this can cause nausea, bloating, and prolonged fullness, particularly during dose escalation

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