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How can disulfide bonding lead to reduced activity

Therefore, accelerated oxidation of biomolecules acts both as a product and causal for disease manifestation which is further exacerbated by failure of antioxidant system and loss of redox sensing capabilities of chaperone DJ-1 18,19

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The proximal colonic motor response to rectal mechanical and chemical stimulation

2014;48 Suppl 1:S18-22