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doi: 10.1172/JCI116442 196 OhgamiNNagaiRMiyazakiAIkemotoMAraiHHoriuchiSet al

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345 The accumulation of proNGF and downregulation of TrkA (pro-survival signal) levels favor the predominance of pro-apoptotic signaling mediated by p75 NTR , further promoting the degeneration of basal forebrain cholinergic neurons

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