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Abdominal pain Headache Low blood sugar Constipation Fatigue Nausea Vomiting Diarrhea Dizziness Acid Reflux For the majority of individuals, symptoms tend to be mild and resolve spontaneously over time

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Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should not use GLP-1 medications due to a theoretical risk of thyroid tumors observed in animal studies

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As noted, endogenous GLP-1 has a very short half-life of 12 min because it is rapidly degraded by the enzyme DPP-4, which results in low systemic levels

You should not take phentermine if you have a history of heart disease, stroke, congestive heart failure, or uncontrolled high blood pressure