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Filipcikova R, Oborna I, Brezinova J, et al

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10.1016/j.pneurobio.2015.09.008 Prog

The above formulation will be incorporated in the transdermal patch Example 6 : In-vitro release of example 2 Table 10: In vitro release of batch G of example 2 Figure 5 provides In-vitro release of transdermal gel prepared according to the present invention as provided in example 2 - batch G

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In a mouse model of AD, probiotic treatment with Lactobacillus and Bifidobacterium strains improved cognitive function and reduced amyloid-beta deposition, supporting a neuroprotective role of gut microbiota modulation ( 3.6.4.2 Dietary interventions Stroke not only causes direct brain injury but also induces systemic changes including gut dysbiosis and impaired intestinal barrier function, which can contribute to infection risk and influence stroke severity and recovery