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Concomitant medications particularly other glucose-lowering agents such as insulin or sulphonylureas may increase the risk of hypoglycaemia when used alongside retatrutide

They treat type 2 diabetes, aid weight loss, and may improve cardiovascular health

In my clinical opinion, patients with obesity or metabolic disease should not delay treatment

In another study, chronic GLP1-S treatment in rodent models produced sustained weight loss, primarily by shrinking meal size rather than reducing the number of meals

A recent meta-analysis of data from seven double-blind randomized controlled trials with tirzepatide lasting at least 26 weeks confirmed the cardiovascular safety of tirzepatide in patients with T2D (77)

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