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peptide degrades rapidly at room temperature (~25% activity loss after 24 hours at 4 C) [7]

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The search for GLP- 1 receptor agonists to treat T2DM was sparked by studies showing the insulinotropic and glucose-lowering effects of GLP- 1 in beta cells, as well as the hyperglycemic effects of GLP- 1 receptor antagonism [44]

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