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After TBI, mitochondrial membrane disruption not only critically impairs oxidative phosphorylation at the site of electron transport but also activates downstream signaling pathways (ROS, caspases, calpains, etc.) that lead to cell death [76]

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Psychometric evaluation included internal consistency reliability, factorial validity, Bland-Altman analysis of instrument agreement, convergent validity through correlation analysis, and known-groups validity across and health status subgroups