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10.1080/17460441.2018.1457644 28 CuervoA

Here is what to expect post-approval: | Insurance Type | Expected Coverage | Timeline | |---------------|-------------------|----------| | Employer-sponsored (large) | Likely with prior auth | 6-12 months post-approval | | Employer-sponsored (small) | Variable | 12-24 months post-approval | | Medicare Part D | Possible after CMS review | 12-18 months post-approval | | Medicaid | State-dependent | 18-36 months post-approval | | ACA Marketplace | Varies by plan | 12-24 months post-approval | **Key factor:** The Treat and Reduce Obesity Act and evolving anti-obesity medication (AOM) coverage policies may accelerate insurance adoption

Supporting this, data from our functional enrichment analysis of the transcriptome revealed notable upregulation of oxidative phosphorylation and the oxidative damage response in hepsin / mice treated with saline (data not shown)

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