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It does not mimic, replace, or replicate the mechanism of GLP-1 medications

Glucagon-like peptide-1 receptor activation in the nucleus accumbens core suppresses feeding by increasing glutamatergic AMPA/kainate signaling

Even when netted out for rebates and payment assistance, a year of treatment can approach five figures

Conversely, while the metabolic burden in the reproductive subtype is relatively lighter, ovulatory dysfunction and hyperandrogenic symptoms are more prominent, suggesting that the mode of benefit may differ in these patients (51, 54)

None of these is a footnote each is a reason a real prescribing decision would require individual medical assessment rather than a generic protocol

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