However, GMP certification covers manufacturing process rather than product efficacy
Effect sizes were unavailable due to study heterogeneity, and no serious adverse effects were reported
Mechanisms and therapeutic targets
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Gastrointestinal Cytoprotection In its original gastric biology context, BPC-157 promotes mucosal integrity through prostaglandin-independent mechanisms, modulates enteric neuron and glial cell activity, counteracts NSAID-induced intestinal permeability, and demonstrates organoprotective activity across the alimentary canal from oesophagus to colon in a range of injury models including ethanol, aspirin, and restraint stress-induced lesions
However, many questions remain about their control and modulation of repair, and it appears that their effects depend on many determinants, including timing, levels, specific binding to receptors, and interaction with other factors
