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Compared to placebo, which showed only a 4.5% reduction, the higher doses delivered statistically significant improvements

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In a clinical trial involving 205 individuals with metastatic NSCLC, who tested positive for high PD-L1 and had no abnormal EGFR or ALK genes, those treated with Tecentriq lived longer (20.2 months) compared to those receiving platinum-based chemotherapy (13.1 months)

The F statistic for all instrument variants was over 74, indicating no bias from weak instruments (Supplementary Table S3)

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301 In addition, arginase 1 (Arg1) administration to activated T cells leading to arginine starvation can block T cell glycolysis