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After incubation of hemolyzed total blood with DTT, we observed a conjugation rate of GSH with CDNB higher than that found in the absence of reducing treatment, suggesting the presence of a significant, not spurious amount of oxidized e-GST (Figure 2a)

Key Takeaways 24.2% weight loss at 48 weeks with 12mg dose, the highest efficacy seen in any GLP-1 class medication trial 93% of participants on 12mg achieved 15% weight loss

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T2D was induced by administration of a high-fat diet for 10 weeks, then injection of a single dose of streptozotocin (STZ)

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