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Clinical trials with melatonin registered at for the treatment of adult patients with cancer In this review, the potential mechanisms of the complex and diverse antineoplastic properties of melatonin have been described

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Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]

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