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Vomiting: Less common than nausea but occurs in some patients

With expedited approval, some products ultimately achieved successful P&MA outcomes due to strong clinical profiles and confirmed effectiveness

This means they are far more sensitive to these drugs in a way that humans generally are not

Seli E, Sakkas D, Scott R, et al

The normal pathways for the synthesis of 2-HG utilize 2-oxoglutarate (-ketoglutarate) or -hydroxybutyrate (GHB) as the substrate

In addition, we tested for co-localization with expression quantitative trait loci in the locus, and identified none that colocalized with the GWAS signal (Supplementary Information)