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Data availability The authors declare that data supporting the findings of this study are available within the article and its Supplementary Information files and from the corresponding author upon reasonable request

The coordinated copper ion enables researchers to investigate metal-mediated biochemical processes within controlled laboratory systems while maintaining a defined and reproducible molecular framework

Animal research from 2016 found that milk thistle extract improved immunity

The majority of reactions require reducing conditions in which stable Cbl (III) is reduced

Topical GHK-Cu may cause tingling or flushing at higher concentrations (above 2%)

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