Such issues highlight the need for a comprehensive toolkit that spans subcortical and cortical surface SCAN targets, incorporating both invasive and non-invasive methods, such as DBS, low- and high-intensity focused ultrasound, TMS and electrical cortical stimulation 25,38,95,96 (Extended Data Fig
For example, chronic alcohol feeding in diethylnitrosamine (DEN)-induced HCC mice leads to reduced antitumor CD8+ T cells and an increase in tumor-associated macrophages (TAMs), which tend to polarize toward the M2 phenotype after alcohol exposure (89)
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Some patients report strong early suppression that stabilizes
