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The correct amount helps avoid adverse effects and potential interactions with GLP-1 medications

doi:10.2147/CCID.S128339

Substrate selection Utilizing Certara's Simcyp Simulator V23, we performed PBPK modeling to examine the impact of GLP1RAassociated delays in GI motility on the pharmacokinetics of atorvastatin, metformin, metoprolol, ethinyl estradiol, and digoxin

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Because the brain has the highest mitochondrial energy demand of any organ, even subtle changes in mitochondrial energy production preferentially can affect brain function