The company argued that an injunction wouldnt protect patients because they would likely be harmed if the court were to enjoin FDAs shortage decision and greenlight further compounding. The evidence submitted to the FDA to prove that the shortage remains also wasnt sufficient, Novo argued, pointing to patient reports from online reporting systems without any meaningful data integrity controls and screenshots purporting to show unavailability of approved drugs. In any event, FDA rightly concluded that localized supply disruptions may exist even when there is not a nationwide drug shortage, Novo wrote
Patients on tirzepatide who are also taking metformin (a common combination in type 2 diabetes) have slightly elevated risk of lactic acidosis under severe dehydration, so vigilance matters
39,41 When possible, providers should avoid prescribing prednisolone and dexamethasone
The cost of one vial, and our peptide cost calculator can help you budget is far less than weeks of using degraded medication that provides no benefit
Behind every approval or denial is a checklist
But while there is a lot of this kind of anecdotal data, there remains a dearth of research on microdosing