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Especially, FBD3 showed nearly identical potency and efficiency as fentanyl in either cAMP inhibition or Gi recruitment assays but had very limited -arrestin recruitment activity (Figure 6b-c)

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CrossRef Effects of bariatric surgery on neurological disturbances and quality of life in patients with metabolic dysfunction-associated steatotic liver disease and obesity: a prospective longitudinal study Concepcin Gmez, Juan Jos Gallego Roig, Mara Lapea, Clara Alfaro-Cervell, Alessandra Fiorillo, Adri Lpez-Gramaje, Raquel Alfonso Ballester, Norberto Casinello, Mara Capilla Lozano, Mara Desamparados Escudero-Garca, Cristina Montn, Amparo Urios Surgery for Obesity and Related Diseases .2026