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In specific secondary analyses we examined the impact of antidepressant use, measured based on drug container inspection of medications used in the past month, classified according to the World Health Organization Anatomical Therapeutic Chemical classification: selective serotonin reuptake inhibitors (N06AB), tricyclic antidepressants (N06AA) and other less commonly prescribed medications (N06AX, N06AF, N06AG)

10.1038/s41374-020-0404-9 45 IgwebuikeC.YaglomJ.HuitingL.FengH.CampbellJ

However, DR-10,624, a GLP-1/GCG/fibroblast growth factor 21 (FGF-21) triple agonist is under investigation for individuals with severe hypertriglyceridemia (not limited to individuals with obesity

Selon les auteurs, ces rsultats suggrent que leffet protecteur de ces mdicaments passerait principalement par un effet bnfique pour les vaisseaux sanguins, ce qui pourrait amliorer loxygnation du cerveau, protgeant sa sant

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