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Likewise, activation of POMC/CART neurons promotes a sense of fullness and indirectly hinders the secretion of two peptides known for stimulating hunger: neuropeptide Y (NPY) and agouti-related peptide (AgRP) [12]

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6.5 The Strategic Map Summarized across the four transactions, the triple-agonist deal map splits along two axes: modality (peptide injection versus oral small molecule versus oral peptide) and geography (in-house U.S./EU discovery versus Chinese licensing versus Korean licensing)