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Protein globularization during folding

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RGN-352 was shown to be safe and well-tolerated with no serious drug-related adverse events reported (PMID: 20536472) Phase 2 AMI trial (incomplete): RegeneRx designed a Phase 2 proof-of-concept trial (NCT01311518) to evaluate RGN-352 in approximately 75 patients with acute ST-segment elevation myocardial infarction (heart attack)

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Bile acids are synthesized from cholesterol and serum levels of 7-hydroxy-4-cholesten-3-one (C4), an intermediate product of this process, reflect the activity of bile acid synthesis (168)

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