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The addition of niacinamide does not contraindicate use in diabetes, though monitoring blood glucose closely is important

Quality of life improvements prove equally significant

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The treatment typically starts with a low dose, which is then incrementally increased based on individual factors such as weight, response to the medication, and overall health

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As GLP-1 RAs show neuroprotective effect such as reduce infarct volume and neurological deficits in normoglycemic model against stroke without affecting blood glucose levels, they may be potential candidates for the treatment of stroke alone