A 2.6% reduction in hip bone mineral density and a 2.1% reduction at the lumbar spine in 52 weeks (Hansen et al., 2024), combined with up to 10.9% lean mass loss over 72 weeks (Look et al., 2025), means that patients on GLP-1 therapy need a comprehensive musculoskeletal protection plan from day one
But while the world is going to just continue to yell about the weight loss numbers, I want to discuss the fact that this drug seems to be about as close to a metabolic fix it all, unlike anything weve seen before
Skipping it isn't just a missed nutritional opportunity it may actually reduce the hormonal response your medication is trying to support
These approaches are common among doctors who specialize in medical weight management, and as such, medical record data can be studied to inform future guidelines and standardization about maintenance-phase dosing in particular
Six months ago I weighed 238 lb and had tried every diet imaginable
In most but not all studies, a small increase in white blood cell count (approximately 200 cells/microL difference in WBC vs