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In the STEP 1 trial extension, participants regained roughly two-thirds of their prior weight loss within a year of stopping semaglutide

We take the guesswork and the risk out of the equation

I didnt really want to keep snacking like I used to, she says

Kalkan et al

Tirzepatide is also administered as a once-weekly injection and follows a similar gradual dose-escalation schedule

Key gaps No semaglutide trial programme publicly reports validated vaginal symptom patient-reported outcomes (dryness scales, dyspareunia scores, pH/microbiome endpoints) in regulatory product information, limiting incidence estimation for vaginal endpoints