When should I talk to a healthcare provider
So we asked the BuzzFeed Community a simple but important question: If you've been on a GLP-1, what's a side effect no one warned you about
The pharmacologic exploitation of GLP-1 signaling has led to two major therapeutic strategies: DPP-4 inhibitors, which prolong endogenous GLP-1 activity, and GLP-1 RAs, which mimic or enhance GLP-1 action while resisting enzymatic degradation (13)
Both effects decrease over time with ongoing treatment because of tolerance and tachyphylaxis.8,20e24 After 8 weeks of treatment with liraglutide (a long-acting GLP-1 RA), gastric emptying returned to near baseline values.23 Of note, contrasting effects have been found with shorter acting GLP-1 RAs that retained delayed gastric emptying over time.23 Although associated with reduced oral intake and a beneficial loss of weight in overweight and obese patients, these effects might worry anaesthesiologists given the theoretically increased risk of aspiration
The honest assessment: Replenza is a good starting point for GLP-1 users who want simple, convenient nutritional support and do not want to research individual supplements
When they find them, they launch an immune attack
