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Peer review Peer review information Nature Metabolism thanks Timo Mller and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Have blood tests shown low B12 levels or anaemia

Verify your reconstitution math and actual concentration before increasing dose most non-response cases trace to calculation errors or degraded peptide rather than true pharmacological resistance

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[7] It should not be used in individuals with hormone-sensitive tumors, such as prostate cancer or breast cancer, due to the risk of stimulating tumor growth through increased androgen or estrogen production

Leggio L, Patern G, Vivarelli S, Bonasera A, Pignataro B, Iraci N, et al