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Histologic examination is necessary to achieve a conclusive diagnosis (109,110)

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Sample clustering was outlined in an explorative PCA combined with loading plots and differential analysis, which highlighted (in light blue) the compounds (Supplementary Table 2) having a log2 fold change higher than 0.5 and a negative log10 of the p -value higher than 0.05 (Supplementary Figure 2a)

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Nephrology 23, 867875