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In Gpx4 knockout cells, GCH1 overexpression can significantly protect cells from ferroptosis, and GPX4 and glutathione levels are not affected by GCH1 overexpression

It helps to reduce oxidative stress and inflammation, which are key factors in the development of heart disease

A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening

Reinfections of healthcare workers led to mild L-C19 symptoms, since most were younger than 65 (179)

2D Ligand interaction diagram of GSH with GPX4 U46C , GPX4 K48A , or GPX4 K48L in their individually top covalent-docking pose (top right and bottom panels)

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