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The cold environment inhibits hydrolysis, oxidation, and deamidation reactions that would otherwise destroy peptide bonds and biological activity
The findings were published on Oct
CJC 1295 without DAC (also called Modified GRF 1-29) carries amino acid substitutions at positions 2, 8, 15, and 27 that resist DPP-IV cleavage, giving a half-life of roughly 30 minutes
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doi: 10.1089/jmf.2005.8.113 60 KettleHLouisPHoltropGDuncanSHFlintHJ