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Importantly, as the chief brain source of APOE, astrocytes, especially those expressing the APOE4 allele, promote A aggregation, tau pathologies, BBB breakdown, and cerebrovascular dysfunctions (Wang M

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Because this is still an investigational compound, we frame the science honestly: what is genuinely studied, and what remains unknown

FIGURE 7 4.5 Multimodal synergistic therapy As mentioned above, we clearly recognize that GSH-responsive and -exhausting metal nanomedicines have a prominent effect on cancer therapy

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