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The persistence of effects without continuous receptor occupation suggests DSIP may trigger gene expression changes rather than requiring constant pharmacological presence

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On admission day, patients underwent an interview including questions on alcohol consumption such as daily quantity and type of alcohol (beer, wine, liquor/distilled spirits) and age at onset of alcohol use

Eur Respir J 24 : 994999 Balzar S, Chu HW, Strand M, Wenzel S 2005 Relationship of small airway chymase-positive mast cells and lung function in severe asthma

Oral bioavailability in humans is limited