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ONC201 induces p53-independent apoptosis and cell cycle arrest in hematological malignancies and leukemic stem/progenitor cells by inducing ER stress and mTOR inhibition

Acknowledgements This work is supported by grants PI15/01857, PI18/01659 and CIBER Fragilidad y Envejecimiento Saludable (CIBERFES) of Instituto de Salud Carlos III (ISCIII), Ministerio de Economa y Competitividad (MINECO), Spain and European Union (EU)

It would be irresponsible to write any of this without naming the tradeoffs honestly