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RKIP regulates Raf1 kinase activity, and consequently MAPK signaling, a pathway involved in mediating the antiproliferative effects of SS, and furthermore inhibits G protein receptor kinase 2, possibly affecting SSTRs internalization and degradation (63)

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doi:10.1016/j.amjhyper.2004.07.020

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La evidencia clnica directa se limita actualmente a una serie no controlada de cinco pacientes tratadas con exenatida y a una comunicacin en formato resumen sobre una paciente tratada con tirzepatida 8,9

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