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References Hayes, J

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Image analysis was performed through Zeiss 510 META confocal microscope and processed with LSM image browser

The pathogenesis of DN involves a variety of factors, such as altered haemodynamics, oxidative stress, and inflammation, and studies from animal models suggest that mitochondrial dysfunction plays an important role in the development of DN

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Intravenous administration of dopamine (the only approved route of administration) or the D1-like receptor agonist fenoldopam are positive inotropes that lead to rapid recovery in these acute conditions (Doggrell, 2002