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However, a meta-analysis reported that the use of NAC showed no significant improvement in pregnancy rate, serum LH level, fasting insulin, and LH/follicle-stimulating hormone (FSH) ratio despite that the BMI and total testosterone were significantly reduced (138)

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Also, strategies for treatment need to be investigated

In control mice, Rikenellaceae , Dentinobacteriaceae , and particularly Lactobacillaceae were dominant, accounting for 26.72, 9.12, and 41.65% of total sequences, respectively

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