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Active Weight Loss Phase (Months 3-12) After initiation, most people spend 6 to 12 months in active weight loss at maintenance doses (1mg or 2mg weekly), achieving the majority of their total weight loss during this phase

These reports do not establish how common the experience is or prove that tirzepatide is the direct cause

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The 10mg vial suits researchers running the Phase 2 low-dose 1mg cohort (10 weeks of weekly dosing from a single vial), the early-escalation weeks of any higher cohort (the 2mg initiation period across the 4mg/8mg/12mg cohorts uses 8mg total over 4 weeks), or pilot research where a minimal commitment is preferred before scaling to the 20mg or 30mg formats

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The supplement approach operates on an entirely different speed scale