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Another type of post-translational modification is methylation by arginine methyltransferases (PRMTs), in which arginine can be methylated to either monomethylated arginine or dimethylated arginine

In fibrotic liver tissues, the inactivation of the Hippo pathway results in the aberrant activation of YAP/TAZ and their translocation into the nucleus, thereby initiating a cascade of gene programs that promote the activation of hepatic stellate cells and drive the progression of liver fibrosis [46]

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