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What happens in your body after the first GLP-1 dose The moment a GLP-1 receptor agonist enters your bloodstream, a cascade begins

GLP-1 RAs improve glycemic control, promote cardiovascular and renal protection, and reduce all-cause mortality [2, 3]

Its a term that has been popularized on social media, said Amanda Velazquez, MD, director of Obesity Medicine at Cedars-Sinai

Effects of GLP-1 and GIP receptor agonists include: Stimulating insulin secretion in response to food (glucose-dependent) Reducing inappropriate glucagon release, lowering hepatic glucose output (GLP-1 enhances the sensitivity of alpha cells to glucose , resulting in more glucose-appropriate glucagon secretion) When blood glucose is high, insulin secretion is stimulated and glucagon secretion is inhibited

Gastroenterology (2015) 149(2):37988

Theyve also recently added brand-name Wegovy and Zepbound for patients who want FDA-approved options