Among other things, it is involved in the functioning of the heart, nervous system, eyes, and muscles, supports the fluid balance of cells, and contributes to protection against oxidative stress
We previously found that BMAL1 binds to the Mat2a promoter in adipocytes and regulates its expression, while deletion of Bmal1 reduces both MAT2A protein and SAM abundance 8
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Cancer cells and normal cells potentially use different food sources, Harris explained, and we discovered how cancer cells, specifically, break down this antioxidant and use it as fuel. The new role for glutathione is notable, Harris said, because until now, most scientists who study glutathione have focused on the way it can prevent or repair cell damage, rather than its ability to feed cancer cells
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