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In some embodiments, after the first stage, the dispersed microparticles in the solvent immiscible fluid medium are isolated from the fluid medium by any convenient means of separation

Tirzepatide causes gastrointestinal symptoms including nausea, vomiting, diarrhea, and constipation in a substantial percentage of users, particularly during dose escalation phases

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As noted in the Effective Dates section below, while this requirement will become effective January 1, 2026, we will delay enforcement to April 1, 2026