Furthermore, FABP4 KO mice have decreased tumor burden and metastasis compared to WT mice when injected with ovarian cancer cells (25), suggesting FABP4 may be an attractive target for cancer
doi: 10.1002/prot.21766 48
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The synthesis method of the Cagrilintide comprises the third step of preparing 200mL of cracking reagent, adding the full-protection peptide under an ice bath condition, returning to room temperature after 0.5h, continuing to react for 2h, adding anhydrous ether for precipitation after the reaction is finished, performing centrifugal precipitation for multiple times, adding 300mL of ether each time, and drying to obtain the Cagrilintide product
It decreases body weight, as a result of increasing in glutathione production