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A summary of the research was presented this week at the International Meeting for Autism Research in Baltimore

It is not intended for human or animal administration outside of a controlled research setting, and this article should not be read as guidance for personal use

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J Endocrinol Invest 34:265

Lipidomic results suggest that phosphatidylethanolamine (PE) containing arachidonic acid (AA) is the key membrane phospholipid for the occurrence of oxidation-driven ferroptosis ( System Xc- is a heterodimeric cell surface amino acid reverse transmitter

MBOAT1 could selectively decrease cellular levels of PE-PUFA (polyunsaturated fatty acid), which is the preferred substrate for peroxidation to induce ferroptosis, and thus suppresses ferroptosis in a GPX4 -independent manner 54