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examined the effect of liraglutide on NAFLD in a high-fat diet (HFD) SpragueDawley (SD) rat model for 4 weeks and reported improvement in hepatic steatosis, lobular inflammation, and ballooning
doi: 10.1016/S2213-8587(22)00077-8 75 DahlDOnishiYNorwoodPHuhRBrayRPatelHet al
Discontinuation due to adverse events: 4.1% (4mg) / 6.9% (9mg) / 11.3% (12mg) vs
Peptides, or small protein fragments, are often too unstable to use as drugs, but in this study, the researchers also developed a way to stabilize the molecules and help them get into target cells
Selected publications: Targeted liquid chromatography-tandem mass spectrometry analysis of proteins Proteomics, 2021