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The role of dutasteride is more acceptable in the secondary preventive setting

The typical 2-cysteine residue PRXs react with H 2 O 2 to form a SO intermediate, which condenses with the resolving cysteine of the adjacent PRX to form an intermolecular dimer

Eur J Pharmacol 2020;888:173574

Subsequently, during proliferative and remodeling phases, TIMP expression increases in coordination with new matrix deposition, preventing premature degradation of nascent collagen and elastic fiber networks

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