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Other intranasal preparations being explored in Parkinsons include dopamine, one using gene therapy, a vitamin E loaded naringenin, stem cells, glial cell-derived neurotrophic factor (GDNF), carnosine, BDNF, intranasal insulin, rotigotine, and estradiol

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The active factor turned out to be a small tripeptide that tightly bound copper

Semaglutide slows gastric emptying, which could theoretically increase colon pressure in susceptible patients, but clinical flare-up rates during GLP-1 therapy remain poorly studied